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Large-Conductance Calcium-Activated Potassium Channels

More information in Books or onNLM PubMed
Definition: A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.     
Examples Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channel beta Subunits 		Other names Maxi K Channels; Large Conductance Calcium Activated Potassium Chan; MaxiK Channels; Maxi-K Channels; Big K Channels; BK Channels
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
termitomycesphin B  0   *Glucosylceramides Large-Conductance Calcium-Activated Potassium Channels/agonists. Mol Membr Biol 2011 Feb;28(2):145-54
termitomycesphin A  0   *Glucosylceramides Large-Conductance Calcium-Activated Potassium Channels/agonists. Mol Membr Biol 2011 Feb;28(2):145-54
slo-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Large-Conductance Calcium-Activated Potassium Channels.
slo protein, Drosophila  0   *Drosophila Proteins *Large-Conductance Calcium-Activated Potassium Channels.
Kcnu1 protein, mouse  0   *Large-Conductance Calcium-Activated Potassium Channels. J Biol Chem 1998 Feb 6;273(6):3509-16

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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