encyclopedia of medical concepts
ψ 
ψ 

bcl-X Protein

More information in Books or onNLM PubMed
Definition: A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.  Don't confuse with the closely related BCL2-ASSOCIATED X PROTEIN    Other names bcl2 Like 1 Protein; bcl Xshort Protein; bcl Xlong Protein; bcl Xbeta Protein; bcl Xb Protein; bcl Xalpha Protein; bcl Xa Protein; bcl XS Protein; bcl XL Protein; bcl X Protein; bcl2L1 Protein; bcl2-Like 1 Protein; bcl-x(beta) Protein; bcl-Xshort Protein; bcl-Xlong Protein; bcl-Xbeta Protein; bcl-Xb Protein; bcl-Xalpha Protein; bcl-Xa Protein; bcl-X(S) Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-methoxyantimycin  0   Antimycin A/*analogs & derivatives bcl-X Protein/antagonists & inhibitors. Mol Cancer Ther 2007 Jul;6(7):2073-80
4-(3-dimethylamino-1-phenylsulfanylmethylpropylamino)-N-(4-(4,4-dimethylpiperidin-1-yl)benzoyl)-3-nitrobenzenesulfonamide  0   *Aniline Compounds *Sulfonamides bcl-X Protein/antagonists & inhibitors. J Med Chem 2006 Feb 9;49(3):1165-81
N-(4'-fluorobiphenyl-4-ylcarbonyl)-3-nitro-4-(2-phenylsulfanylethylamino)benzenesulfonamide  0   *Aniline Compounds *Sulfonamides bcl-X Protein/antagonists & inhibitors. J Med Chem 2006 Jan 26;49(2):656-63
Bcl2l1 protein, rat  0   *bcl-X Protein.
Bcl2l1 protein, mouse  0   *bcl-X Protein.
BCL2L1 protein, human  0   *bcl-X Protein.
bcl2l protein, zebrafish  0   *Zebrafish Proteins *bcl-X Protein.
bcl-XL protein, Xenopus  0   *Xenopus Proteins *bcl-X Protein.

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy