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Papillomavirus E7 Proteins

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Definition: ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells and lead to NEOPLASTIC CELL TRANSFORMATION. Papillomavirus E7 proteins have been shown to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN and certain cyclin-dependent kinase inhibitors.      Other names Oncogene Proteins, E7; E7 Proteins, Papillomavirus; Oncogene Protein E7, Papillomavirus; E7 Oncogene Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
oncogene protein E7, human papilloma virus type 45  0   *Papillomavirus E7 Proteins. Oncogene 2006 Sep 28;25(44):5953-9
E7 protein, Human papillomavirus type 31  0   *Papillomavirus E7 Proteins. EMBO J 2005 May 18;24(10):1821-30
oncogene protein E7, Human papillomavirus type 16  0   *Papillomavirus E7 Proteins Protein-Tyrosine Kinases Transcription Factors Zinc Fingers Human papillomavirus 16. J Virol 1989;63(6):2650

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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