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beta-Carotene 15,15'-Monooxygenase

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Definition: A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL. It was formerly characterized as EC 1.13.11.21 and EC 1.18.3.1.      Other names beta Carotene Cleaving Enzyme; beta Carotene 15,15' Monooxygenase; beta Carotene 15,15' Dioxygenase; Dioxygenase, Carotene; Cleaving Enzyme, beta-Carotene; 15,15'-Monooxygenase, beta-Carotene; 15,15'-Dioxygenase, beta-Carotene; beta-Carotene Cleaving Enzyme; beta-Carotene 15,15'-Dioxygenase; beta, beta-Carotene-15,15'-Monooxygenase; beta, beta-Carotene-15,15'-Dioxygenase; Carotene Dioxygenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RPE65 protein, Ciona  EC 1.18.3.1   *beta-Carotene 15,15'-Monooxygenase. Photochem Photobiol. 2006 Nov-Dec;82(6):1468-74
ninaB protein, Drosophila  EC 1.14.99.36   *Drosophila Proteins *beta-Carotene 15,15'-Monooxygenase.
Bcmo1 protein, mouse  EC 1.14.99.36   *beta-Carotene 15,15'-Monooxygenase.
BCMO1 protein, human  EC 1.14.99.36   *beta-Carotene 15,15'-Monooxygenase.
Bcdo protein, rat  EC 1.14.99.36   *beta-Carotene 15,15'-Monooxygenase.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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