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Gelsolin

More information in Books or onNLM PubMed
Definition: A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.      Other names Serum Actin Inhibitory Protein; Gelsolin Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
gelsolin (173-242), human  0   *Peptide Fragments *Gelsolin. Biochemistry 2011 Apr 5;50(13):2486-98
gelsolin (160-169)  0   *Peptide Fragments *Gelsolin. J Leukoc Biol 2008 Feb;83(2):245-53
Scinla protein, zebrafish  0   *Gelsolin *Zebrafish Proteins Crystallins. FASEB J 2007 Oct;21(12):3318-28
gelsolin-related protein, 125-kDa  0   *Gelsolin Protozoan Proteins. Mol Biol Cell 1999 Jan;10(1):161-78
gelsolin (150-169)  0   *Peptide Fragments *Gelsolin. Biophys J 1995 Dec;69(6):2695-702
flightless I protein, Drosophila  0   *Gelsolin *Drosophila Proteins. Genetics 1995 Nov;141(3):1049-59
scinderin  0   *Gelsolin. FEBS Lett 1990;268(1):209
brevin  0   *Gelsolin Actins Contractile Proteins. FEBS Lett 92(1):85;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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