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Receptors, Prostaglandin E

More information in Books or onNLM PubMed
Definition: Cell surface receptors which bind prostaglandins with a high affinity and trigger intracellular changes which influence the behavior of cells. Prostaglandin E receptors prefer prostaglandin E2 to other endogenous prostaglandins. They are subdivided into EP1, EP2, and EP3 types based on their effects and their pharmacology.  note specific subtypes are available    Other names Prostaglandin E Receptors; PGE2 Receptors; PGE Receptors; Receptor, Prostaglandin E; E Receptors, Prostaglandin; E Receptor, Prostaglandin; Prostaglandin E Receptor; PGE Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
sodium 6-((5-chloro-2-(((4-chloro-2-fluorophenyl)methyl)oxy)phenyl)methyl)-2-pyridinecarboxylate  0   *Nicotinic Acids Receptors, Prostaglandin E/antagonists & inhibitors. Bioorg Med Chem Lett. 2009 May 1;19(9):2599-603
N-((4-(5,9-diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo(3,4-g)quinolin-7-yl)-3-methylbenzyl)sulfonyl)-2-(2-methoxyphenyl)acetamide  0   *Quinolines *Sulfonamides Receptors, Prostaglandin E/antagonists & inhibitors. J Pharmacol Exp Ther 2008 May;325(2):425-34
9-deoxy-9-chloro-15-deoxy-16-hydroxy-17,17-trimethylene-19,20-didehydroprostaglandin E2  0   Dinoprostone/*analogs & derivatives Receptors, Prostaglandin E/agonists. Br J Pharmacol 2004 Apr;141(7):1141-50
ONO 8711  0   *Bicyclo Compounds *Hexanoic Acids Receptors, Prostaglandin E/antagonists & inhibitors. Cancer Res 1999 Oct 15;59(20):5093-6
TEI 4343  0   Epoprostenol/*analogs & derivatives Receptors, Prostaglandin E/agonists. Biochem J 1997 Mar 1;322(Pt 2):597-601
TEI 3356  133906-74-8 2-Pentalenepentanoic acid, 1,3a,4,5,6,6a-hexahydro-5-hydroxy-6-(4-hydroxy-4-methyl-1-octenyl)-, (3aS-(3aalpha,5beta,6alpha(1E,4R*),6aalpha))  Epoprostenol/*analogs & derivatives Receptors, Prostaglandin E/agonists. Prostaglandins Leukot Essent Fatty Acids 1991 Dec;44(4):237-9
11-deoxy-16-phenoxy-17,18,19,20-tetranorprostaglandin E1  80558-61-8 Cyclopentaneheptanoic acid, 2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxo-, (1R-(1alpha,2beta(1E,3R*)))  Alprostadil/*analogs & derivatives Prostaglandins E, Synthetic Receptors, Prostaglandin E/agonists.
Pharma Action Anti-Ulcer Agents 		Prostaglandins 1981;22(2):167

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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