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Genes, APC

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Definition: Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.     
See Also Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Gardner Syndrome 		Other names Genes, Adenomatous Polyposis Coli; Gene, APC; APC Genes; APC Gene
 
SubstanceCAS Registry & nameCategoriesSource
adenomatous polyposis coli protein 2  0   *Cytoskeletal Proteins Neoplasm Proteins Genes, APC Adenomatous Polyposis Coli Protein. Curr Biol 1999 Jan 28;9(2):105-8

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