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Uric Acid

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Definition: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.     
Pharmacological Action Antioxidants 		Other names Urate; Urate, Sodium Acid; Urate, Sodium; Urate, Potassium; Urate, Monosodium; Urate, Ammonium Acid; Urate Monohydrate, Sodium; Urate Monohydrate, Monosodium; Monohydrate, Sodium Urate; Monohydrate, Monosodium Urate; Acid, Uric; Acid Urate, Sodium; Acid Urate, Ammonium; Trioxopurine; Sodium Urate Monohydrate; Sodium Urate; Sodium Acid Urate Monohydrate; Sodium Acid Urate; Potassium Urate; Monosodium Urate Monohydrate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-hydroxyisourate  0   Uric Acid/*analogs & derivatives. Biochemistry 1998 Aug 18;37(33):11651-9
Lgals9 protein, rat  0   *Organic Anion Transporters Uric Acid.
SLC22A12 protein, human  0   *Organic Anion Transporters *Organic Cation Transport Proteins Uric Acid.
9-methyluric acid  55441-71-9   Uric Acid/*analogs & derivatives. Proc Natl Acad Sci U S A 2002 Dec 10;99(25):16303-8
1,7-dimethyl-8-oxoenprofylline  0   Uric Acid/*analogs & derivatives. Biochem Biophys Res Commun 2001 Nov 16;288(5):1212-7
8-oxoenprofylline  0   Uric Acid/*analogs & derivatives. Biochem Biophys Res Commun 2001 Nov 16;288(5):1212-7
2,6-dithiouric acid  0   Uric Acid/*analogs & derivatives. Chem Res Toxicol 1996 Dec;9(8):1298-304
urate transporter  0   *Organic Anion Transporters Uric Acid. J Biol Chem 1997 Jan 3;272(1):617-25
1,3,7,9-tetramethyluric acid  2309-49-1   Uric Acid/*analogs & derivatives. Mutat Res 1992 Oct;269(2):259-67
3,7-dimethyluric acid  13087-49-5 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-3,7-dimethyl  Uric Acid/*analogs & derivatives. Xenobiotica 1990;20(8):823
1,7-dimethyluric acid  33868-03-0   Uric Acid/*analogs & derivatives. Clin Pharmacol Ther 1987;42(2):157
9-N-ribofuranosyluric acid 5'-monophosphate  21082-31-5   *Ribonucleotides Uric Acid/*analogs & derivatives. Nucleic Acids Symp Ser 1985;(16):157
9-N-ribofuranosyluric acid  21082-30-4   *Ribonucleosides Uric Acid/*analogs & derivatives. Nucleic Acids Symp Ser 1985;(16):157
urate-binding alpha 2-globulin protein, human  0   *Carrier Proteins Alpha-Globulins Uric Acid. Adv Exp Med Biol 1984;165 Pt A:163
1,3,7-trimethyluric acid  5415-44-1   Uric Acid/*analogs & derivatives. Life Sci 1983;33(12):1173
3-N-ribosyluric acid 5'-monophosphate  87004-59-9 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-3-(5-O-phosphono-beta-D-ribofuranosyl)  *Ribonucleotides Uric Acid/*analogs & derivatives. Comp Biochem Physiol [b] 1983;75(3):495
1,3-dimethyluric acid  944-73-0   Uric Acid/*analogs & derivatives. Eur J Clin Pharmacol 1981;20(6):435
1-methyluric acid  708-79-2   Uric Acid/*analogs & derivatives. Biopharm Drug Dispos 1981;2(1):31
2-thiouric acid  15986-31-9   Uric Acid/*analogs & derivatives. MGG 1981;181(1):107
Reye's syndrome serum factor  0   *Uric Acid Reye Syndrome. Biochem Biophys Res Commun 1980;94(1):381
5-hydroxy-pseudouric acid  6960-28-7 Urea, (hexahydro-5-hydroxy-2,4,6-trioxo-5-pyrimidinyl)  Uric Acid/*analogs & derivatives. Experientia 1980;36(1):78
4,5-dihydro-4,5-dihydroxyuric acid  67708-22-9 1H-Purine-2,6,8(3H)-trione, tetrahydro-4,5-dihydroxy  Uric Acid/*analogs & derivatives. Experientia 1980;36(1):78
uric acid riboside  2124-54-1 7,9-dihydro-3-beta-D-ribofuranosyl-1H-purine- 2,6,8(3H)-trione  *Ribonucleosides Uric Acid/*analogs & derivatives. Hemoglobin 3(1):47;1979; J Anim Sci 41(6):1674;1975
6-thiouric acid  2002-60-0   Uric Acid/*analogs & derivatives. Biochem Med 12(3):234;1975

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