Triethylenephosphoramide (definition)

encyclopedia of medical concepts

ψ	Triethylenephosphoramide

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Definition: An insect chemosterilant and an antineoplastic agent.

a chemosterilant & alkylating antineoplastic
Pharmacological Action Antineoplastic Agents, Alkylating
Examples Thiotepa

Other names TEPA

Substance	CAS Registry & name	Categories	Source
N,N,N',N'-bis(1,2-ethanediyl)-N''-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinylaminocarbonyl)phosphoric triamide	96662-64-5	Triethylenephosphoramide/*analogs & derivatives.	Life Sci 1985;36(15):1473
iodobenzotef	4119-81-7 N-(bis(1-aziridinyl)phosphinyl)-2-iodobenzamide	Triethylenephosphoramide/*analogs & derivatives.	Farmakol Toksikol 41(6):719;1978
fluorobenzotepa	726-92-1	Triethylenephosphoramide/*analogs & derivatives.	Nat Cancer Instit Monograph 45:235;1977
diiodobenzotepa	4460-32-6	Triethylenephosphoramide/*analogs & derivatives.	Biull Eksp Biol Med 1979;88(10):424; Nat Cancer Instit Monograph 45:235;1977; Vopr Onkol 1979;25(9):53
benzo-tepa	4110-66-1 N-(bis(1-aziridinyl)phosphinyl)benzamide	Triethylenephosphoramide/*analogs & derivatives.	Eksp Med Morfol 13(4):237;1974; Farm Zh 2:83;1976; Farm Zh 3(5):50;1976; Farm Zh 3:48;1976; Farmatsiia 27(2):63;1978; Klin Med (Mosk) 52(5):50;1974; Natl Cancer Inst Monogr 45:235;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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