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Prostaglandin Endoperoxides, Synthetic

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Definition: Synthetic compounds that are analogs of the naturally occurring prostaglandin endoperoxides and that mimic their pharmacologic and physiologic activities. They are usually more stable than the naturally occurring compounds.  coord IM with specific syn prostaglandin (NIM); DF: PG ENDOPEROXIDES SYN    Other names Prostaglandin Endoperoxide Analogs; Endoperoxides, Synthetic Prostaglandin; Endoperoxide Analogues, Prostaglandin; Analogues, Prostaglandin Endoperoxide; Synthetic Prostaglandin Endoperoxides; Prostaglandin Endoperoxide Analogues
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
prostaglandin H2 9-cyclic ether  0   *Prostaglandin Endoperoxides, Synthetic *Prostaglandin H2. Am Rev Respir Dis 1990;141(2):456
prostaglandin H2 methyl ester  63942-75-6   *Prostaglandin Endoperoxides, Synthetic *Prostaglandin H2. Biochem Biophys Res Commun 1984;120(2):512
U 44069  56985-32-1   *Prostaglandin Endoperoxides, Synthetic. Prostaglandins Med 1980;5(6):469
11,9-epoxymethanoprostaglandin H1  72517-81-8 2-Oxabicyclo(2.2.1)heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, (1alpha,4alpha,5beta,6alpha(1E,3S*))-(+-)  *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
9,11-epoxymethanoprostaglandin H1  0   *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
11,9-epoxycarbonylprostaglandin H1  72580-46-2 2-Oxabicyclo(2.2.1)heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-3-oxo-, (1alpha,4alpha,5beta,6alpha(1E,3S*))-(+-)  *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
9,11-epoxycarbonylprostaglandin H1  0   *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
9,11-azo-13-oxa-15-hydroxyprostanoic acid  0   *Prostaglandin Endoperoxides, Synthetic. J Med Chem 1979;22(11):1402
9,11-iminoepoxyprosta-5,13-dienoic acid  0   *Prostaglandin Endoperoxides, Synthetic. Biochim Biophys Acta 573(2):238;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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