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Progesterone Reductase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione. EC 1.1.1.145.      Other names 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase; Reductase, Progesterone; Dehydrogenase, 5-Ene-3 beta-hydroxysteroid; Dehydrogenase, 3 beta-Hydroxy-delta-5-Steroid; 5 Ene 3 beta hydroxysteroid Dehydrogenase; 3 beta Hydroxy delta 5 Steroid Dehydrogenase; Steroid delta(5)-3 beta-ol Dehydrogenase; 5-Ene-3 beta-hydroxysteroid Dehydrogenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3 beta-hydroxysteroid dehydrogenase type II  EC 1.1.1.145   *Progesterone Reductase Isoenzymes.
3 beta-hydroxysteroid oxidoreductase-delta(5) 3-ketosteroid isomerase  0   *Multienzyme Complexes *Progesterone Reductase *Steroid Isomerases. Cancer 38(1):56;1976; Endocrinology 102(3):665;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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