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Peptide Chain Elongation, Translational

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Definition: A process of GENETIC TRANSLATION, when an amino acid is transferred from its cognate TRANSFER RNA to the lengthening chain of PEPTIDES.  coordinate with specific peptide; for protein biosynthesis on the ribosome only; for non-ribosomal biosynthesis use PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT   
See Also Peptide Elongation Factors; Peptidyl Transferases; Protein Synthesis Inhibitors
Other names Protein Translational Elongation; Genetic Translation Elongation; Elongation, Protein Translational; Elongation, Protein Translation; Elongation, Protein Biosynthesis; Elongation, Genetic Translation; Biosynthesis Elongation, Protein; Translational Peptide Chain Elongation; Translational Elongation, Protein; Translation Elongation, Protein; Translation Elongation, Genetic; Protein Translation Elongation; Protein Chain Elongation, Translational; Protein Biosynthesis Elongation; Chain Elongation, Peptide, Translational
 
SubstanceCAS Registry & nameCategoriesSource
MDL 20828  98930-79-1 2-Propenamide, N-(2-hydroxy-1-(((4-hydroxyphenyl)sulfinyl)methyl)ethyl)-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)  Sparsomycin/*analogs & derivatives Peptide Chain Elongation, Translational Peptidyl Transferases/antagonists & inhibitors. Biochem Biophys Res Commun 1990;166(2):673
tRNA-protein transferase, amino acyl  EC 2.3.2.-   *Aminoacyltransferases Peptide Chain Elongation, Translational. Biochem J 126(2):409;1972; Curr Top Cell Regul 13:1;1978; J Mol Cell Cardiol 5(2):185;1973; Mol Cell Biochem 2(1):3;1973; Seikagaku 51(1):1;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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