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Guanosine Tetraphosphate

More information in Books or onNLM PubMed
Definition: Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I.  /biosyn /physiol permitted; DF: PPGPP    Other names Guanosine 5' Diphosphate 3' Diphosphate; Guanosine 3' Diphosphate 5' Diphosphate; 5'-Diphosphate, Guanosine 3'-Diphosphate; 5'-Diphosphate 3'-Diphosphate, Guanosine; 3'-Diphosphate, Guanosine 5'-Diphosphate; 3'-Diphosphate 5'-Diphosphate, Guanosine; Tetraphosphate, Guanosine; Guanosine 5'-Diphosphate 3'-Diphosphate; Guanosine 3'-Diphosphate 5'-Diphosphate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-thioguanosine-3',5'-(bis)pyrophosphate  0   *Thionucleotides Guanosine Tetraphosphate/*analogs & derivatives. J Biol Chem 2001 Jan 12;276(2):1220-5
adenosine 5',5'''-triphosphoguanosine-3'''-diphosphate  56878-12-7   Guanosine Tetraphosphate/*analogs & derivatives. J Bacteriol 1988;170(5):2344

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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