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Etomidate

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Definition: Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.     
Pharmacological Action Anesthetics, Intravenous; Hypnotics and Sedatives 		Other names R26490; R 26490; Radenarkon; R-26490; Hypnomidate; EthomidateDrugs* : AMIDATE; ETOMIDATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ethyl 1-(1-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)ethyl)-1H-imidazole-5-carboxylate  0   Diazomethane/*analogs & derivatives Etomidate/*analogs & derivatives. J Med Chem 2010 Sep 9;53(17):6432-44
carboetomidate  0   *Pyrroles Etomidate. Anesthesiology. 2010 Mar;112(3):637-44
methoxycarbonyletomidate  0   Etomidate/*analogs & derivatives. Anesthesiology 2009 Aug;111(2):240-9
iodophenyl metomidate  0   Etomidate/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2008 Apr 10;51(7):2244-53
acyl azide etomidate  0   Etomidate/*analogs & derivatives. J Biol Chem 2007 Apr 20;282(16):12038-47
4-benzoylbenzyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate  0   *Benzophenones Etomidate/*analogs & derivatives. J Med Chem 2006 Aug 10;49(16):4818-25
4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate  0   Diazomethane/*analogs & derivatives Etomidate/*analogs & derivatives. J Med Chem 2006 Aug 10;49(16):4818-25
azietomidate  0   Etomidate/*analogs & derivatives Ligands. J Med Chem 2003 Mar 27;46(7):1257-65
metomidate  5377-20-8 1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, methyl ester  Etomidate/*analogs & derivatives Carbon Radioisotopes Radioactive Tracers.
R 8110  109872-40-4 1H-Imidazole-5-carboxylic acid, 1-(1-(4-fluorophenyl)ethyl)-, ethyl ester, monohydrochloride  Etomidate/*analogs & derivatives. Res Vet Sci 1987;42(2):200

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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