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Estriol

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Definition: A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.     
Examples Estetrol
Other names 17 Epiestriol; 16,17 Epiestriol; 16 alpha Hydroxy Estradiol; 16 Hydroxyestradiol; 16 Epiestriol; Ovestin; Epiestriol; 17-Epiestriol; 16-alpha-Hydroxy-Estradiol; 16-Hydroxyestradiol; 16-Epiestriol; 16,17-Epiestriol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
nilestriol  0   Estriol/*analogs & derivatives. Hua Xi Yi Ke Da Xue Xue Bao 2000 Mar;31(1):65-7
dehydropregnanetriol  0   Estriol/*analogs & derivatives Biological Markers. Prenat Diagn 2001 Mar;21(3):207-12
dehydroestriol  0   Estriol/*analogs & derivatives Biological Markers. Prenat Diagn 2001 Mar;21(3):207-12
3-methoxymethyl-16,17-epiestriol-O-cyclic sulfone  0   *Cyclic S-Oxides Estriol/*analogs & derivatives. Nucl Med Biol 1996 Oct;23(7):911-5
estratriene-2,3,14,15,16,17-hexaol  176219-89-9   Estriol/*analogs & derivatives. Biosci Biotechnol Biochem 1996 Mar;60(3):405-10
hormonin  79275-73-3   *Estradiol *Estriol *Estrone Drug Combinations Tablets Estrogen Replacement Therapy. Eur J Vasc Endovasc Surg 1996 Apr;11(3):347-8
3,16,17-trihydroxyestra-1,3,5(10)-trien-15-yl-2'-acetamido-2'-deoxyglucopyranoside  0   Estriol/*analogs & derivatives Glucosamine/*analogs & derivatives. Steroids 1995 Mar;60(3):277-84
estriol 3,17-dipropionate  104202-88-2   Estriol/*analogs & derivatives. Horm Res 1991;35(6):234-8
estriol 3,17-dihexanoate  104202-96-2   Estriol/*analogs & derivatives. Horm Res 1991;35(6):234-8
17-cyano-16,17-epoxy-1,3,5(10)estratrien-3-ol  100702-71-4   Estriol/*analogs & derivatives. J Steroid Biochem 1989;32(1A):85
2-methoxyestriol  1236-72-2   Estriol/*analogs & derivatives. Nippon Naibunpi Gakkai Zasshi 1987;63(5):712
6-hydroxyestriol  14507-00-7   Estriol/*analogs & derivatives. Clin Chem 1986;32(7):1397
estriol 17-sulfate  42028-21-7   Estriol/*analogs & derivatives Estrogens, Conjugated (USP). J Steroid Biochem 1986;24(1):357
3-methoxy-14,15-methyleneestra-1,3,5-triene-17-ol  68247-73-4   Estriol/*analogs & derivatives. Exp Clin Endocrinol 1985;85(2):138
estradiol, estriol drug combination  0   *Estradiol *Estriol Drug Combinations. Acta Obstet Gynecol Scand 1984;63(7):655
estriol receptor  0   *Receptors, Estrogen Estriol. J Steroid Biochem 1984;21(2):163
estriol-6-carboxymethyloxime-aminobutyl-N-ethylisoluminol  0   Estriol/*analogs & derivatives Luminescent Measurements. Steroids 1983;42(2):123
16-methylamino-3-methoxy-1,3,5-estratrien-17-ol  90193-07-0 Estra-1,3,5(10)-trien-17-ol, 3-methoxy-16-(methylamino)-, (16alpha,17beta)  Estriol/*analogs & derivatives. Steroids 1982;40(6):615
estra-1,3,5(10)-triene-3,7,17-triol  3398-11-6   Estriol/*analogs & derivatives. Gen Comp Endocrinol 1983;49(3):490
estriol-3-carboxymethyl ether  69260-14-6 Acetic acid, (((16alpha,17beta)-16,17-dihydroxyestra-1,3,5(10)-trien-3-yl)oxy)  Estriol/*analogs & derivatives. Clin Chim Acta 1983;128(2-3):223
2,4-dinitroestriol  84605-03-8 Estra-1,3,5(10)-triene-3,16,17-triol, 2,4-dinitro-, (16alpha,17beta)  Estriol/*analogs & derivatives. Clin Chem 1982;28(9):1968
estriol 17-glucuronide  7219-89-8   Estriol/*analogs & derivatives. J Chromatogr 1982;282(1):13
estriol-16alpha-glucuronyl-6-aminobutyl-ethyl-isoluminol  76648-58-3 beta-D-Glucopyranosiduronamide, (16alpha,17beta)-3,17-dihydroxyestra-1,3,5(10)-trien-16-yl N-(4-(ethyl(1,2,3,4-tetrahydro-1,4-dioxo-6-phthalazinyl)amino)butyl)  Estriol/*analogs & derivatives Antigens. J Steroid Biochem 1981;14(9):941
estriol glucuronide  28808-07-3   Estriol/*analogs & derivatives. J Steroid Biochem 1981;14(9):935
Trisequens  66100-41-2   *Estradiol *Estriol Drug Combinations Norethindrone/*analogs & derivatives.
Pharma Action Contraceptives, Oral
Drug Ther Bull 1981;19(16):63
estriol 3-sulfate  481-95-8   Estriol/*analogs & derivatives. Am J Obstet Gynecol 1980;138(8):1137
estriol 3-sulfate 16-glucuronide  4661-65-8   Estriol/*analogs & derivatives. Am J Obstet Gynecol 1980;138(8):1137
estriol 3-glucuronide  2479-91-6 (16 alpha,17 beta)-16,17-dihydroxyestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronic acid  Estriol/*analogs & derivatives Estrogens, Conjugated (USP). J Clin Endocrinol Metab 50(1):137;1980
16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol  472-57-1   Estriol/*analogs & derivatives. J Biol Chem 254(21):10720;1979
estriol-3-methyl ether  1474-53-9   Estriol/*analogs & derivatives. Ind J Exptl Biol 15:16;1977
4-hydroxyestriol  60021-32-1 Estra-1,3,5(10)-triene-3,4,16,17-tetrol, (16alpha,17beta)  Estriol/*analogs & derivatives Estrogens, Catechol. Steroids 28(5):733;1976
estriol-16 alpha-(beta-D-glucuronide)  1852-50-2   Estriol/*analogs & derivatives Estrogens, Conjugated (USP). Am J Obstet Gynecol 125(6):841;1976; J Chromatogr 145(3):478;1978; J Clin Endocrinol Metab 1979;50(1):137; Steroids 1979;34(4):445
quinestradol  1169-79-5   Estriol/*analogs & derivatives. Ann Ostet Ginecol Med Perinat 96(2):83;1975; Arzneim Forsch 26(4):583;1976; Cancer Res 38(11):4012;1978; Endocrinol 98(1):179;1976
estriol-16,17-disuccinyl-bovine serum albumin  0   *Serum Albumin, Bovine Estriol/*analogs & derivatives Estrogens, Conjugated (USP). Am J Obstet Gyn 123(7):700;1975
2,4,17 alpha-d(3)-estriol 3-glucuronoside  0   Estriol/*analogs & derivatives Estrogens, Conjugated (USP). Chem Pharm Bull 22(12):3002;1975
estriol-4-azobenzoic acid  40761-62-4 Benzoic acid, 4-(((16alpha,17beta)-3,16,17-trihydroxyestra-1,3,5(10)-trien-4-yl)azo)  Estriol/*analogs & derivatives. J Steroid Biochem 6(5):703;1975
2-(4'-carboxyphenylazo)estriol  57266-76-9 Benzoic acid, 4-(((16alpha,17beta)-3,16,17-trihydroxyestra-1,3,5(10)-trien-2-yl)azo)  Estriol/*analogs & derivatives. J Clin Endocrinol Metab 40(6):970;1975
estriol succinate  514-68-1   Estriol/*analogs & derivatives. Acta Obstet Gynecolog Scand 56(4):363;1977; Am J Obstet Gyn 123(7):700;1975; Ginecol Obstet Mex 35(207):1;1974; Indian J Physiol Pharm 21(3):195;1978
2-hydroxyestriol  1232-80-0 2,16 alpha-dihydroxyestradiol /OD/ estra-1,3,5(10)- triene-2,3,16 alpha,17 beta-tetrol  Estriol/*analogs & derivatives Estrogens, Catechol. Chem Pharm Bull (Tokyo) 23(7):1613;1975; J Endocrinol 1979;82(1):131; J Steroid Biochem 5(1):1;1974; J Steroid Biochem 6(7):1187;1975; Steroids 28(5):733;1976
18-homoestriol  19882-03-2   Estriol/*analogs & derivatives. Drug Metab Disp 1(2):537;1973
estriol-6-(O-carboxymethyl)oxime  37654-41-4 Acetic acid, ((((16alpha,17beta)-3,16,17-trihydroxyestra-1,3,5(10)-trien-6-ylidene)amino)oxy)  Estriol/*analogs & derivatives. J Steroid Biochem 6(5):703;1975; Steroids Lipid Res 3(2):82;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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