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Diethylstilbestrol

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Definition: A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)  DF: DES   
Pharmacological Action Carcinogens; Estrogens, Non-Steroidal
Examples Hexestrol 		Other names Stilbestrol; Estrogen, Stilbene; Co Pharma Brand of Diethylstilbestrol; Tampovagan; Stilbene Estrogen; Gerda Brand of Diethylstilbestrol; Distilb+¿ne; Diethylstilbestrol, Disodium Salt; Diethylstilbestrol, (Z)-Isomer; Co-Pharma Brand of Diethylstilbestrol; Apstil; Agostilben; APS Brand of DiethylstilbestrolDrugs* : DIETHYLSTILBESTROL; STILBESTROL; STILBETIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cajanine  0   Diethylstilbestrol/*analogs & derivatives Phytoestrogens. Yao Xue Xue Bao 2007 Apr;42(4):386-91
diethylstilbestrol glutamate  0   *Glutamates Diethylstilbestrol/*analogs & derivatives. J Drug Target 2006 Jul;14(6):437-43
N-(4'-hydroxy-3'-iodophenethyl)-6-(4-O-diethylstilbestryl)hexanamide  140683-97-2   *Iodobenzenes Diethylstilbestrol/*analogs & derivatives. Steroids 1992 Jan;57(1):27-31
diethylstilbestrol monomethyl ether  7773-60-6   Diethylstilbestrol/*analogs & derivatives. Mutat Res 1991;263(4):269
3,4'-dihydroxy-alpha,beta-diethylstilbene  133683-37-1   *Diethylstilbestrol Isomerism. Chem Pharm Bull (Tokyo) 1991;39(1):218
diethylstilbesterol-DNA adduct  0   *Diethylstilbestrol *DNA Adducts. Carcinogenesis 1991;12(3):385
3,3'-diallyldiethylstilbestrol  4870-88-6   Diethylstilbestrol/*analogs & derivatives. Biol Cell 1989;66(1-2):29
diethylstilbestrol monophosphate  47341-71-9 Phenol, 4-(1-ethyl-2-(4-hydroxyphenyl)-1-butenyl)-, 1-(dihydrogen phosphate), (E)  Diethylstilbestrol/*analogs & derivatives. J Cancer Res Clin Oncol 1986;111(2):110
diethylstilbestrol quinone  5664-37-9 2,5-Cyclohexadien-1-one, 4,4'-(1,2-diethyl-1,2-ethanediylidene)bis  Diethylstilbestrol/*analogs & derivatives. Biochem Pharmacol 1983;32(24):3711
percutatrine  0   *Diethylstilbestrol *Estrone *Tissue Extracts Drug Combinations Ointments. Helv Paediatr Acta 1983;38(4):361
3,3',5,5'-tetrafluorodiethylstilbestrol quinone  86321-57-5 2,5-Cyclohexadien-1-one, 4,4'-(1,2-diethyl-1,2-ethanediylidene)bis(2,6-difluoro)  Diethylstilbestrol/*analogs & derivatives. Cancer Res 1983;43(6):2678
1-hydroxypseudodiethylstilbestrol  68034-40-2 Phenol, 4,4'-(1-ethyl-2-(2-hydroxyethylidene)-1,2-ethanediyl)bis-, (Z)  Diethylstilbestrol/*analogs & derivatives Isomerism. Steroids 1982;39(6):681
2,3,4,5-bis(epoxy)-3,4-bis(4'-acetoxyphenyl)hexane  82699-02-3 Phenol, 4,4'-(3,3'-dimethyl(2,2'-bioxirane)-2,2'-diyl)bis-, diacetate, (2alpha(2'R*,3'S*),3beta)  Diethylstilbestrol/*analogs & derivatives. Arch Pharm (Weinheim) 1982;315(6):515
2,3-epoxy-3,4-bis(4'-acetoxyphenyl)-4-hexene  82699-01-2 Phenol, 4-(1-(2-(4-(acetyloxy)phenyl)-3-methyloxiranyl)-1-propenyl)-, acetate, (2alpha(E),3beta)  Diethylstilbestrol/*analogs & derivatives. Arch Pharm (Weinheim) 1982;315(6):515
diethylstilbestrol-3,4-oxide  78969-61-6 Oxirane, 2,3-bis(4-ethoxyphenyl)-2,3-diethyl  Diethylstilbestrol/*analogs & derivatives. J Cancer Res Clin Oncol 1981;100(3):247
3,4-bis(3'-methoxy-4'-hydroxyphenyl)-3-hexene  78765-33-0 Phenol, 4,4'-(1,2-diethyl-1,2-ethenediyl)bis(2-methoxy)-, (E)  Diethylstilbestrol/*analogs & derivatives. Steroids 1981;37(3):327
3,4-bis(4-hydroxyphenyl)-3-hexenol  62080-79-9 Benzenepropanol, 4-hydroxy-gamma-(1-(4-hydroxyphenyl)propylidene)-, (E)  Diethylstilbestrol/*analogs & derivatives. Steroids 1981;37(3):327
3,4,4'-trihydroxy-alpha,alpha'-diethylstilbene  71113-07-0 1,2-Benzenediol, 4-(1-ethyl-2-(4-hydroxyphenyl)-1-butenyl)-, (E)  Diethylstilbestrol/*analogs & derivatives. Steroids 1981;37(3):327
3,4-bis(3',3'-dimethoxyphenyl)-3-hexene  82846-25-1 Benzene, 1,1'-(1,2-diethyl-1,2-ethenediyl)bis(3,4-dimethoxy)-, (E)  Diethylstilbestrol/*analogs & derivatives. Steroids 1981;37(3):327
diethylstilbestrol monoglucuronide  2408-40-4   Diethylstilbestrol/*analogs & derivatives. CRC Crit Rev Biochem 1981;10(3):171
3,3'-dihydroxy-alpha,beta-diethylstilbene  80149-87-7   Diethylstilbestrol/*analogs & derivatives. J Cancer Res Clin Oncol 1980;97(2):167
1,2-diethyl-1,3-bis(4-methoxyphenyl)-1-propene  74886-24-1   Diethylstilbestrol/*analogs & derivatives. Indian J Exp Biol 1980;18(6):557
alpha,alpha-dihydroxydiethylstilbestrol  7507-01-9   Diethylstilbestrol/*analogs & derivatives. Arch Biochem Biophys 1980;202(1):318
diethylstilbestrol pinacolone  18922-13-9 3-hexanone, 4,4-bis(4-hydroxyphenyl)  Diethylstilbestrol/*analogs & derivatives. Biochem J 1980;185(1):129
diethylstilbestrol epoxide  6052-82-0 phenol, 4,4'-(2,3-diethyl-2,3-oxiranediyl)bis  Diethylstilbestrol/*analogs & derivatives. Biochem J 1980;185(1):129
3,5,3',5'-tetrafluorodiethylstilbestrol  71292-84-7   Diethylstilbestrol/*analogs & derivatives. Steroids 33(5):543;1979
diethylstilbestrol bisglucuronide  53915-13-2 beta-D-Glucopyranosiduronic acid, (1,2-diethyl-1,2-ethenediyl)di-4,1-phenylene bis-, (E)  Diethylstilbestrol/*analogs & derivatives. Hoppe Seylers Z Physiol Chem 359(12):1803;1978
iodoacetyldiethylstilbestrol  66463-48-7 Acetic acid, iodo-, 4-(1-ethyl-2-(4-hydroxyphenyl)-1-butenyl)phenyl ester, (E)  Diethylstilbestrol/*analogs & derivatives. Eur J Biochem 84:267;1978
4-acetyl-diethylstilbestrol  0   Diethylstilbestrol/*analogs & derivatives. Eur J Biochem 84:275;1978
pseudodiethylstilbestrol  39011-86-4   *Diethylstilbestrol Isomerism. Science 194(4269):1059;1976
stilbostat  15470-58-3   *Nitrogen Mustard Compounds Diethylstilbestrol/*analogs & derivatives. Endocrinologie 15(2):127;1977; Neoplasma 21(1):101;1974; Neoplasma 23(4):363;1976; Neoplasma 24(5):553;1977
N-hydroxy-4'-hydroxy-7,7'-diethyl-trans-N-4-stilbenylacetamide  52498-24-5 N-(4-(1-ethyl-2-(4-hydroxyphenyl)-1-butenyl)phenyl)-N-hydroxyacetamide  Diethylstilbestrol/*analogs & derivatives. J Med Chem 17(4):386;1974
N-acetoxy-4'-hydroxy-7,7'-diethyl-N-4-stilbenylacetamide  52569-57-0   Diethylstilbestrol/*analogs & derivatives. J Med Chem 17(4):386;1974
fosfestrol  13425-53-1 alpha,alpha'-diethyl-4,4'-stilbenediol diphosphate  Diethylstilbestrol/*analogs & derivatives.
Pharma Action Antineoplastic Agents, Hormonal 		Cancer Res 38(11):3702;1978; Laryngol Rhinol Otol (Stuttg) 54(11):871;1975; Lyon Med 226(13):119;1971; Soc Fr Urol 83(1-2):143;1977; Urology 7(6):598;1976STILPHOSTROL
dimestrol  130-79-0 alpha,alpha'-diethyl-4,4'-dimethoxystilbene  Diethylstilbestrol/*analogs & derivatives.
diethylstilbestrol dipropionate  37221-14-0 alpha,alpha'- diethyl-4,4'-stilbenediol dipropionate  Diethylstilbestrol/*analogs & derivatives.
Pharma Action Estrogens 		Endokrinologie 52(5/6):373;1967/68; IARC Monogr Eval Carcinog Risk Chem Hum 1979;21:173

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