encyclopedia of medical concepts
ψ 

Dantrolene

More information in Books or onNLM PubMed
Definition: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.     
Pharmacological Action Muscle Relaxants, Central 		Other names Sodium, Dantrolene; Dantrolene Sodium; DantriumDrugs* : DANTROLENE SODIUM; DANTRIUM
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GIF-0430  0   Dantrolene/*analogs & derivatives. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1289-94
GIF-0667  0   Dantrolene/*analogs & derivatives. Bioorg Med Chem Lett 2005 Mar 1;15(5):1289-94
GIF-0162  0   Dantrolene/*analogs & derivatives. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1289-94
GIF-0373  0   Dantrolene/*analogs & derivatives. Bioorg Med Chem Lett 2005 Mar 1;15(5):1289-94
N-((3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl))benzyl)dantrolene  0   Dantrolene/*analogs & derivatives. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3259-61
GIF 0185  0   Dantrolene/*analogs & derivatives. Br J Pharmacol 2001 Oct;134(4):729-36
GIF 0082  0   Dantrolene/*analogs & derivatives. Br J Pharmacol 2001 Oct;134(4):729-36
azidodantrolene  0   Dantrolene/*analogs & derivatives Ligands Tritium Photoaffinity Labels. J Med Chem 1999 Jun 3;42(11):1872-80
aminodantrolene  0   Dantrolene/*analogs & derivatives. J Biol Chem 1995 Aug 4;270(31):18465-72
F 490  41515-09-7   Dantrolene/*analogs & derivatives. J Chromatogr 1982;231(2):401
5-hydroxydantrolene  52130-25-3   Dantrolene/*analogs & derivatives. J Chromatogr 1982;228(12):404
5-chloro-2-pyrimidinyl dantrolene  0   Dantrolene/*analogs & derivatives. J Pharm Sci 64(2):337;1975

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy