encyclopedia of medical concepts
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Vidarabine Phosphate
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Definition
: An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.
a vidarabine ester antimetabolite; DF: note short X ref
Pharmacological Action
Antimetabolites
;
Antiviral Agents
Other names
Vidarabine Monophosphate; Arabinofuranosyladenine Monophosphate; Adenine Arabinoside Monophosphate; Ara-
AMP; Phosphate, Vidarabine; Monophosphate, Vidarabine; Monophosphate, Arabinofuranosyladenine; Monophosphate, Adenine Arabinoside; Ara AMP; 9-
(5-
O-
Phosphono-
beta-
D-
arabinofuranosyl)-
9H-
purin
Substance
CAS Registry & name
Categories
Source
Drugs
*
FLUDAP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Vidarabine Phosphate/analogs & derivatives
Cisplatin
Cytarabine
Dexamethasone.
Leuk Lymphoma 2000 Apr;37(3-4):309-17
lactosaminated polylysine-
adenine arabinoside monophosphate
0
*Amino Sugars
Vidarabine Phosphate/*analogs & derivatives
Polylysine/*analogs & derivatives.
Biochem Pharmacol 1994 Feb 11;47(4):643-50
fludarabine monophosphate
75607-67-9
Vidarabine Phosphate/*analogs & derivatives.
Pharma Action
Antimetabolites, Antineoplastic
;
Immunosuppressive Agents
Cancer Res 1984;44(9):4183
FLUDARABINE PHOSPHATE
;
FLUDARA
;
OFORTA
cyclic 9 beta-
D-
arabinosyladenine 3',5'-
monophosphate
32465-18-2
Vidarabine Phosphate/*analogs & derivatives.
Cancer Res 32(9):1791;1972; J Med Chem 17(3):259;1974
ara-
ATP
3714-60-1 9H-
purin-
6-
amine, 9-
(5-
O-
(hydroxy(hydroxy(phosphonooxy)phosphinyl)phosphinyl)-
beta-
D-
arabinofuranosyl)
Vidarabine Phosphate/*analogs & derivatives.
Antimicrob Ag Chemother 21(1):53;1978; Biochem Biophys Res Commun 81(4):1418;1978; Biochem Pharmacol 1979;28(15):2401; Biochemistry 1980;19(1):215; Biochim Biophys Acta 1979;563(1):150; Cancer Res 1979;39(11):4673; Cancer Res 37:2282;1977; Cancer Res 38(8):2314;1978; Eur J Biochem 79:411;1977; Experientia 32(12):1572;1976; IARC Sci Publ 24(part 2):999;1978; J Biochem (Tokyo) 84(3):727;1978; J Chromatogr 133(2):335;1977
