encyclopedia of medical concepts
ψ

bufalin

under Bufanolides
More information in Books or onNLM PubMed
More on Bufanolides Definition: Cyclopentanophenanthrenes with a 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. They are found in BUFONIDAE and often possess cardiotonic properties.  includes bufenolides, bufatrienolides    Other names Bufadienolides
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bufalin [ bufalin, (3alpha,5beta)-isomer ]
  cardiotonic; powerful anesthetic & one of the active constituents of the Chinese drug ch'an su(senso); in Japan prepared from skin of Bufo bufo garfarizans; RN given refers to (3beta,5beta)-isomer 		465-21-4 3,14-dihydroxy-bufa-20,22-dienolide  *Bufanolides Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors Materia Medica
Pharma Action Antineoplastic Agents; Cardiotonic Agents; Enzyme Inhibitors 		Chem Pharm Bull (Tokyo) 25(1):64;1977; Jap J Pharmacol 24(1):97;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy