Definition: A highly dense subclass of the high-density lipoproteins, with particle sizes below 7 nm. They are also known as nascent HDL, composed of a few APOLIPOPROTEIN A-I molecules which are complexed with PHOSPHOLIPIDS. The lipid-poor pre-beta-HDL particles serve as progenitors of HDL3 and then HDL2 after absorption of free cholesterol from cell membranes, cholesterol esterification, and acquisition of apolipoproteins A-II, Cs, and E. Pre-beta-HDL initiate the reverse cholesterol transport process from cells to liver.
Other names PreBeta HDL; Pre-beta High-Density Lipoproteins; Pre-beta HDL Lipoprotein; Pre beta1 High Density Lipoprotein; Pre beta1 HDL; Pre beta High Density Lipoprotein; Pre beta HDL; Lipoproteins, Pre-beta High-Density; Lipoprotein, Pre beta HDL; High-Density Lipoprotein, Pre-beta; High Density Lipoproteins, Pre beta; High Density Lipoprotein, Pre beta1; HDL, Pre-beta1; HDL, Pre-beta; HDL, Nascent; HDL Lipoprotein, Pre-beta; PreBeta-HDL; Pre-beta1 High-Density Lipoprotein; Pre-beta1 HDL; Pre-beta High-Density Lipoprotein
