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Leukocyte L1 Antigen Complex

More information in Books or onNLM PubMed
Definition: A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.     
Examples Calgranulin A; Calgranulin B 		Other names Migratory Inhibitory Factor Related Protein MRP; L1 Protein, Leukocyte; Calcium Binding Myeloid Protein P8,14; Antigen, L1; Antigen, 27E10; Antigen L1, Myelomonocytic; Myelomonocytic Antigen L1; Migratory Inhibitory Factor-Related Protein MRP; Calprotectin; Calgranulin; Calcium-Binding Myeloid Protein P8,14; 27E10 Antigen; Leukocyte L1 Protein; L1 Antigen

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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