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Genes, erbA

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Definition: Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.  erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA   
See Also Oncogene Proteins v-erbA; Receptors, Thyroid Hormone
Other names v-erbA Oncogene; v-erbA Gene; v erbA Oncogenes; v erbA Genes; erbA-beta Genes; erbA-beta Gene; erbA-alpha Genes; erbA-alpha Gene; erbA beta Genes; erbA beta Gene; erbA alpha Genes; erbA alpha Gene; erbA Gene; c-erbA Proto-Oncogene; c-erbA Gene; c erbA Proto Oncogenes; c erbA Genes; beta Genes, erbA; beta Genes, TR; beta Gene, erbA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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