Definition: Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
lansoprazole [ AG 1749,Abbot Brand of Lansoprazole,Bamalite,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)-1H-benzimidazole,AG-1749,Agopton,Almirall Brand of Lansoprazole,Hoechst Brand of Lansoprazole,Hormona Brand of Lansoprazole,Lanzor,Lederle Brand of Lansoprazole,Monolitum,Ogast,Ogastro,Opiren,Prevacid,Prezal,Pro Ulco,Promeco,Promeco Brand of Lansoprazole,Salvar Brand of Lansoprazole,TAK 390MR,TAK-390MR,TAK390MR,TAP Brand of Lansoprazole,Takeda Brand of Lansoprazole,Takepron,Tecnobio Brand of Lansoprazole,Ulpax,Vinas Brand of Lansoprazole,Wyeth Brand of Lansoprazole,Zoton,dexilant,dexlansoprazole,dexlansoprazole MR,lansoprazol,lansoprazole sulphone,lansor,lanzoprazole ] K+/H+-ATPase antagonist; dexlansoprazole (TAK-390MR) is the enantiomer; structure given in first source
